Report on 640 victims of the Tokyo subway sarin attack.
2001
Resistance lessens after administration of atropine.
OPCW Director-General Shares Incontrovertible Laboratory Results Concluding Exposure to Sarin.
White RF, Steele L, O'Callaghan JP, Sullivan K, Binns JH, Golomb BA, et al. Secure area, establish incident site, and don protective equipment/gear appropriate for hazardous material exposure according to the provider agency protocol 3.
Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs.
Evaluate respiratory function and pulse. A preliminary study on delayed vestibulo-cerebellar effects of Tokyo Subway Sarin Poisoning in relation to gender difference: frequency analysis of postural sway. Patients in critical condition caused by complications of nerve agent poisoning, such as hypoxic brain injury, may require prolonged intensive care.Antidotes for nerve agent toxicity are atropine and pralidoxime.There is also generally no benefit in giving more than three injections of 2-PAM Cl.
Yokoyama K, Araki S, Murata K, et al. Ventilatory distress is a physical finding of systemic exposure and marked resistance to ventilation is expected due to bronchial constriction and spasm. Together they comprise the G-series nerve agents, thus named because German scientists first synthesized them, beginning with GA in 1936.
Atropine and pralidoxime chloride (2-PAM Cl) are antidotes for nerve agent toxicity; however, pralidoxime must be administered within minutes to a few hours following exposure (depending on the specific agent) to be effective.
/viewarticle/936777
As they published their work in a scientific journal, the study’s authors warned that the results “cannot be directly extrapolated to the human situation.”“In July, Emergent leaders ordered that Trobigard sales materials be scrapped and that the device be moved to a portion of the company’s website that lists products in development, the company confirmed.
Observe these patients in the ED or hospital for at least 18 hours.
2001
Effects of low-level exposure to sarin and cyclosarin during the 1991 Gulf War on brain function and brain structure in US veterans. Facts About Nerve Agents Technical Information. Post was not sent - check your email addresses!
Kato T, Hamanaka T. Ocular signs and symptoms caused by exposure to sarin gas. A systems dynamics approach to the efficacy of oxime therapy for mild exposure to sarin gas.
Available at Worek F, Herkert NM, Koller M, Thiermann H, Wille T. Application of a dynamic in vitro model with real-time determination of acetylcholinesterase activity for the investigation of tabun analogues and oximes.
Level A protection should be used until monitoring results confirm the contaminant and the concentration of the contaminant.Decontamination of liquid nerve agent exposure consists of removing all clothing, copiously irrigating with water to physically remove the nerve agent, and then washing the skin with an alkaline solution of soap and water or 0.5% hypochlorite solution (made by diluting household bleach 1:10) to chemically neutralize the nerve agent. If shortness of breath occurs, or breathing is difficult (dyspnea), administer oxygen.